- 2000 　

  • Murata, K., Ishii, N., Takano, H., Miura, S., Ndhlovu, L. C., Nose, M., Noda, T. and Sugamura, K.: Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J. Exp. Med.191: 365-374, 2000
  • Kumaki S, Ishii N, Minegishi M, Ohashi Y, Hakozaki I, Nonoyama S, Imai K, Morio T, Tsuge I, Sakiyama Y, Miyanoshita A, Miura Ji, Mayumi M, Heike T, Katamura K, Takada H, Izumi I, Kamizono J, Hibi S, Sasaki H, Kimura M, Kikuta A, Date Y, Sako M, Tanaka H, Sano K and Sugamura K. Characterization of the gammac chain among 27 unrelated Japanese patients with X-linked severe combined immunodeficiency (X-SCID) Hum. Genet107: 406-408, 2000
  • Asada, H., Ishii, N., Sasaki, Y., Endo, K., Kasai, H., Tanaka, N., Takeshita, T., Tsuchiya, S., Konno, T. and Sugamura, K.: Grf40, a Novel Grb2 Family Member, Is Involved in T-Cell Signaling through Interaction with SLP-76 and LAT. J. Exp. Med., 189: 1383-1390, 1999
  • Kumaki, S., Ishii, N., Minegishi, M., Tsuchiya S., Cosman, D., Sugamura, K. and Konno, T.: Functional role of IL-4 and IL-7 in the development of X-linked severe combined immunodeficiency. Blood93: 607-612, 1999
  • Takeshita, T., Arita, T., Higuchi, M., Asao, H., Endo, Y., Kuroda, H., Tanaka, N., Murata, K., Ishii, N. and Sugamura, K.: STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction. Immunity., 6: 449-457, 1997
  • Sugamura, K., Asao, H., Kondo, M., Tanaka, N., Ishii, N., Ohbo, K., Nakamura, M. and Takeshita, T.: The interleukin 2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID. Annu. Rev. Immunol14: 179-205, 1996
  • Sugamura, K., Asao, H., Kondo, M., Tanaka, N., Ishii, N., Nakamura, M. and Takeshita, T.:  The common gamma chain for multiple cytokine receptors. Adv. Immunol59: 225-277, 1995
  • Kimura, Y., Takeshita, T., Kondo, M., Ishii, N., Nakamura, M., Van Snick, J. and Sugamura, K.: Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex. Int. Immunol7: 115-120, 1995
  • Ishii, N., Takeshita, T., Kimura, Y., Tada, K., Kondo, M., Nakamura, M. and Sugamura, K.: Expression of the interleukin 2 receptor gamma chain on various populations in human peripheral blood. Int. Immunol6: 1273-1277, 1994
  • Ishii, N., Asao, H., Kimura, Y., Takeshita, T., Nakamura, M., Tsuchiya, S., Konno, T., Maeda, M., Uchiyama, T. and Sugamura, K.: Impairment of ligand binding and growth signaling of mutant IL-2 receptor gamma chains in patients with X-linked severe combined immunodeficiency. J. Immunol153: 1310-1317, 1994
  • Kondo M, Takeshita T, Ishii N, Nakamura M, Watanabe S, Arai K, and Sugamura K.: Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4.Science262: 1874-1877, 1993
  • Asao, H., Takeshita, T., Ishii, N., Kumaki, S., Nakamura, M., and Sugamura, K.: Reconstitution of the functional IL-2 receptor complexes on fibroblastoid cells: Involvement of the cytoplasmic domain of the gamma chain in two distinct signaling pathways. Proc. Natl. Acad. Sci. USA90: 4127-4131, 1993
  • Takeshita, T., Asao, H., Ohtani, K., Ishii N., Kumaki, S., Tanaka, N., Munakata, H., Nakamura, M. and Sugamura, K.: Cloning of the gammma chain of the human IL-2 receptor. Science257: 379-382, 1992

連絡先

東北大学大学院医学系研究科免疫学
〒980-8575
仙台市青葉区星陵町2-1

TEL 022-717-8096
FAX 022-717-8097

E-mail
ishiin(ｱｯﾄ)med.tohoku.ac.jp